Confirmation of a prognostic index for patients with metastatic breast cancer treated by endocrine therapy

@article{Robertson1992ConfirmationOA,
  title={Confirmation of a prognostic index for patients with metastatic breast cancer treated by endocrine therapy},
  author={Mr. JFR Robertson and A. Dixon and R. W. Nicholson and I O Ellis and C Elston and R. W. Blamey},
  journal={Breast Cancer Research and Treatment},
  year={1992},
  volume={22},
  pages={221-227}
}
We have previously reported a retrospectively constructed index which can accurately predict survival at the time of diagnosis of symptomatic metastatic breast cancer. The index, derived from a Cox model, is scored: Index score = (4 × Grade) − (6 × ER) + (4 × SIMD) − (0.1 × DFI), where histological grade is scored 1–3 (good, moderate, or poor), oestrogen receptor (ER) is scored 0 (negative) or 1 (positive), site of initial metastasis (SIMD) is scored 1–4 for bone only, lung only, bone and lung… CONTINUE READING

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Prognostic factors in recurrent breast cancer: Relationships to site of recurrence, disease-free interval, female sex steroid receptors, ploidy and histological malignancy grading

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  • 1990
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