Confinement-induced quorum sensing of individual Staphylococcus aureus bacteria.

  title={Confinement-induced quorum sensing of individual Staphylococcus aureus bacteria.},
  author={Eric C. Carnes and Deanna M Lopez and Niles P Donegan and Ambrose Cheung and Hattie Gresham and Graham S. Timmins and C Jeffrey Brinker},
  journal={Nature chemical biology},
  volume={6 1},
It is postulated that in addition to cell density, other factors such as the dimensions and diffusional characteristics of the environment could influence quorum sensing (QS) and induction of genetic reprogramming. Modeling studies predict that QS may operate at the level of a single cell, but, owing to experimental challenges, the potential benefits of QS by individual cells remain virtually unexplored. Here we report a physical system that mimics isolation of a bacterium, such as within an… CONTINUE READING