Confinement and clearance of OCT4 in the porcine embryo at stereomicroscopically defined stages around gastrulation.

@article{Vejlsted2006ConfinementAC,
  title={Confinement and clearance of OCT4 in the porcine embryo at stereomicroscopically defined stages around gastrulation.},
  author={Morten Vejlsted and Hanne Offenberg and Flemming Thorup and Poul Maddox-Hyttel},
  journal={Molecular reproduction and development},
  year={2006},
  volume={73 6},
  pages={709-18}
}
In the areas of developmental biology and embryonic stem cell research, reliable molecular markers of pluripotency and early lineage commitment are sparse in large animal species. In this study, we present morphological and immunohistochemical findings on the porcine embryo in the period around gastrulation, days 8-17 postinsemination, introducing a stereomicroscopical staging system in this species. In embryos at the expanding hatched blastocyst stage, OCT4 is confined to the inner cell mass… CONTINUE READING