Confidence in indirect assessment of foot-and-mouth disease vaccine potency and vaccine matching carried out by liquid phase ELISA and virus neutralization tests.

@article{Robiolo2010ConfidenceII,
  title={Confidence in indirect assessment of foot-and-mouth disease vaccine potency and vaccine matching carried out by liquid phase ELISA and virus neutralization tests.},
  author={Blanca Robiolo and Jos{\'e} Leonardo La Torre and Eduardo Malta Maradei and Claudia Perez Beascoechea and Alejandro Alonso P{\'e}rez and Cristina Seki and Eliana Smitsaart and Norberto A. Fondevila and Eduardo Sanchez Palma and Nesya E. Goris and Kris De Clercq and Nora Marta Mattion},
  journal={Vaccine},
  year={2010},
  volume={28 38},
  pages={
          6235-41
        }
}
The necessity of avoiding the use of animals in vaccine potency testing has been widely recognized. The repeatability and reproducibility of the Expected Percentage of Protection (EPP) as a serological potency surrogate for A24 Cruzeiro foot-and-mouth disease virus (FMDV) strain was assessed, and compared with the results obtained with challenge in the Protection against Podal Generalization (PPG) test. To determine the EPPs, the serum titers obtained by liquid phase blocking competitive ELISA… CONTINUE READING
BETA

Citations

Publications citing this paper.
SHOWING 1-10 OF 10 CITATIONS

Effect of lipoarabinomannan from Mycobacterium avium subsp avium in Freund's incomplete adjuvant on the immune response of cattle

  • Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas
  • 2012
VIEW 1 EXCERPT
CITES BACKGROUND

References

Publications referenced by this paper.
SHOWING 1-10 OF 18 REFERENCES

Updating of the correlation between lpELISA titres and virus challenge for the assessment of the potency of polyvalent aphtovirus vaccines in Argentina

E Maradei, J La Torre, +3 authors A Pedemonte
  • Vaccine
  • 2008
VIEW 10 EXCERPTS
HIGHLY INFLUENTIAL

Updating of the correlation between lpELISA titres and virus challenge for the assessment of the potency of polyvalent aphtovirus vaccines in Argentina

E Maradei, J La Torre, +3 authors A Pedemonte
  • Vaccine
  • 2008
VIEW 10 EXCERPTS
HIGHLY INFLUENTIAL

strain matching by serology

KönigG MattionN, C Seki, E Smitsaart, Robiolo Maradei E
  • 2009

in Argentina

N Goris, T Willems, V Diev, P Merkelbach-Peters, T Vanbinst
  • 2008

in Argentina

N Goris, T Willems, V Diev, P Merkelbach-Peters, T Vanbinst
  • 2008

potency testing in cattle using homologous and heterologous challenge strains : precision of the “ Protection against Podal Generalisation ” test

FA Alonso, RC CasaOlascoaga, +3 authors YL ViannaFilho
  • vaccine
  • 2008

Similar Papers

Loading similar papers…