Cone-shaped lipids increase the susceptibility of phospholipids in bilayers to the action of phospholipases.

  • John Buckley
  • Published 1985 in
    Canadian journal of biochemistry and cell biology…


Addition of cardiolipin or diacylglycerol to dispersions of phosphatidylcholine greatly increased hydrolysis by snake venom or pancreatic phospholipase A2, as well as by a microbial phospholipase. Monogalactosyl diglyceride which, like cardiolipin and diacylglycerol, will form nonbilayer hexagonal II structures also caused an increase in the breakdown of… (More)


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