• Corpus ID: 26544012

Conductometric and 1H NMR determination of the critical micellar concentrations of two oxo-derivatives of cholic acid. Which of the two is more hydrophobic?

@inproceedings{Poa2010ConductometricA1,
  title={Conductometric and 1H NMR determination of the critical micellar concentrations of two oxo-derivatives of cholic acid. Which of the two is more hydrophobic?},
  author={Mihaulj Po{\vs}a and Val{\'e}ria Guzsv{\'a}ny and J{\'a}nos J Csan{\'a}di},
  year={2010}
}
Critical micellar concentrations (CMCs) were determined for two novel promoters of membrane permeability – 7-monoketocholic acid (7-MKC) and 12monoketocholic acid (12-MKC), using two non-invasive (conductometry and H NMR relaxation experiment) methods. Studies by these methods suggest the different aggregation abilities of the investigated bile acid derivatives. In an aqueous solution, 7-MKC has a somewhat lower CMC value (43 mM) than 12-MKC (50 mM). Further, it was found that, in addition to… 

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