Conduction Disturbances and Ventricular Arrhythmias Associated with High-Dose Loperamide

  title={Conduction Disturbances and Ventricular Arrhythmias Associated with High-Dose Loperamide},
  author={Diana Altshuler and Ronald M Goldenberg and David Fridman and Eugene Yuriditsky},
Although loperamide has been widely used for the treatment of diarrhea, there is growing popularity over its abuse potential in alleviating opioid-withdrawal symptoms and achieving euphoria. Toxic levels of loperamide have been associated with life-threatening ventricular tachyarrhythmias and cardiac arrest. We report a case of high-dose loperamide ingestion in a patient presenting initially with unstable bradycardia followed by episodes of polymorphic ventricular tachycardia, and an unmasked… CONTINUE READING
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