Conducted dilations initiated by purines in arterioles are endothelium dependent and require endothelial Ca2+.

@article{Duza2003ConductedDI,
  title={Conducted dilations initiated by purines in arterioles are endothelium dependent and require endothelial Ca2+.},
  author={Tasmia Duza and Ingrid H. Sarelius},
  journal={American journal of physiology. Heart and circulatory physiology},
  year={2003},
  volume={285 1},
  pages={H26-37}
}
The signaling pathways underlying the regulation of vascular resistance by purines in intact microvessels and particularly in communication of remote vasomotor responses are unclear. One process by which remote regions of arterioles communicate is via transmission of signals axially along the vessel wall. In this study, we identified a pathway for local and conducted dilations initiated by purines. Adenosine (Ado) or ATP (bind P1 and P2 purinergic receptors, respectively) was micropipette… CONTINUE READING