Conductances responsible for slow wave generation and propagation in interstitial cells of Cajal.

@article{Koh2003ConductancesRF,
  title={Conductances responsible for slow wave generation and propagation in interstitial cells of Cajal.},
  author={Sang Don Koh and Sean M Ward and Tam{\'a}s Ord{\"o}g and Kenton M. Sanders and Burton Horowitz},
  journal={Current opinion in pharmacology},
  year={2003},
  volume={3 6},
  pages={579-82}
}
Interstitial cells of Cajal (ICC) are a fundamental component of the pacemaker apparatus of the gastrointestinal (GI) tract. ICC generate pacemaker currents that are the basis for slow wave activity in GI muscles. ICC form a network of cells connected by gap junctions that run around and along the phasic regions of the GI tract. ICC possess specialized conductances that allow them to generate pacemaker activity and serve as the pathway for active propagation of slow waves. Pacemaker currents… CONTINUE READING
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