Conductance properties of the Na(+)-activated K+ channel in guinea-pig ventricular cells.

@article{Wang1991ConductancePO,
  title={Conductance properties of the Na(+)-activated K+ channel in guinea-pig ventricular cells.},
  author={Zunzhe Wang and Takashi Kimitsuki and Akinori Noma},
  journal={The Journal of physiology},
  year={1991},
  volume={433},
  pages={241-57}
}
1. The Na(+)-activated K+ channel current was recorded from inside-out membrane patches excised from single ventricular cells of guinea-pig hearts. 2. The single channel current-voltage relations showed inward-going rectification with an asymptotic conductance of 180-210 pS for the inward current at 150 mM [K+]o, when [K+]i was changed between 5.4 and 150 mM. The reversal potential indicated the PNa/PK of about 0.02. 3. The amplitude of outward current was reduced by increasing [Mg2+]i or [Na… CONTINUE READING

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