Conductance fluctuations from the inactivation process of sodium channels in myelinated nerve fibres.

@article{Conti1980ConductanceFF,
  title={Conductance fluctuations from the inactivation process of sodium channels in myelinated nerve fibres.},
  author={Franco Conti and Berthold Neumcke and Wolfgang Nonner and Robert St{\"a}mpfli},
  journal={The Journal of physiology},
  year={1980},
  volume={308},
  pages={217-39}
}
1. Na currents and fluctuations of Na currents were studied under voltage clamp in the same myelinated nerve fibres of Rana esculenta at 13 degrees C. The results were used to test several kinetic models for the gating process of Na channels.2. Long voltage pulses, depolarizing the membrane by 16-48 mV from a hyperpolarizing holding level of - 28 mV, were applied in 4 sec intervals. The d.c. and a.c. components of the membrane current were recorded during the last 328 msec of the 473 msec… CONTINUE READING