Conductance and kinetics of delayed rectifier potassium channels in nodal cells of the rabbit heart.

@article{Shibasaki1987ConductanceAK,
  title={Conductance and kinetics of delayed rectifier potassium channels in nodal cells of the rabbit heart.},
  author={T. Shibasaki},
  journal={The Journal of physiology},
  year={1987},
  volume={387},
  pages={227-50}
}
1. The delayed rectifier K+ current (IK) of single pace-maker cells from the sino-atrial node and the atrioventricular node of the rabbit heart was investigated using the whole-cell and cell-attached configurations of the patch-clamp technique. 2. The activation kinetics of the macroscopic IK were not altered by varying the extracellular K+ concentration ([K+]o) between 5.4 and 150 mM. The amplitude of the tail current of IK, however, was about 10-fold larger at a [K+]o of 150 mM than that at a… CONTINUE READING
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