Conditions for the generation of beta oscillations in the subthalamic nucleus-globus pallidus network.

@article{Holgado2010ConditionsFT,
  title={Conditions for the generation of beta oscillations in the subthalamic nucleus-globus pallidus network.},
  author={Alejo J Nevado Holgado and John R. Terry and Rafal Bogacz},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={2010},
  volume={30 37},
  pages={12340-52}
}
The advance of Parkinson's disease is associated with the existence of abnormal oscillations within the basal ganglia with frequencies in the beta band (13-30 Hz). While the origin of these oscillations remains unknown, there is some evidence suggesting that oscillations observed in the basal ganglia arise due to interactions of two nuclei: the subthalamic nucleus (STN) and the globus pallidus pars externa (GPe). To investigate this hypothesis, we develop a computational model of the STN-GPe… CONTINUE READING
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