Conditioning and opiate withdrawal

@article{Schulteis2000ConditioningAO,
  title={Conditioning and opiate withdrawal},
  author={Gery Schulteis and Serge H Ahmed and Andrew C. Morse and George F. Koob and Barry J. Everitt},
  journal={Nature},
  year={2000},
  volume={405},
  pages={1013-1014}
}
The habitual behaviour of many opiate addicts means that the aversive symptoms of drug withdrawal are frequently experienced in specific environments. Stimuli in these environments acquire some of the negative affective properties of opiate withdrawal through pavlovian conditioning, and subsequent exposure to these stimuli alone can then elicit a conditioned withdrawal response that is often associated with drug craving, drug seeking, and relapse back to compulsive drug use after a long… CONTINUE READING

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