Conditioned medium of human adipose-derived mesenchymal stem cells mediates protection in neurons following glutamate excitotoxicity by regulating energy metabolism and GAP-43 expression

@inproceedings{Hao2014ConditionedMO,
  title={Conditioned medium of human adipose-derived mesenchymal stem cells mediates protection in neurons following glutamate excitotoxicity by regulating energy metabolism and GAP-43 expression},
  author={Peng Hao and Zhanhua Liang and Hua Piao and Xiaofei Ji and Yachen Wang and Yong Liu and Rutao Liu and Jing Liu},
  booktitle={Metabolic Brain Disease},
  year={2014}
}
Glutamate excitotoxicity has been implicated as one of the pathological mechanisms contributing to neuronal cell death and is involved in many neurological disorders. Stem cell transplantation is a promising approach for the treatment of nervous system damage or diseases. Previous studies have shown that mesenchymal stem cells (MSCs) have important therapeutic effects in experimental animal and preclinical disease model of central nervous system pathology. However, it is not well understood… CONTINUE READING
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