Conditioned gaping in rats: a selective measure of nausea.

  title={Conditioned gaping in rats: a selective measure of nausea.},
  author={Linda A Parker and Cheryl L. Limebeer},
  journal={Autonomic neuroscience : basic & clinical},
  volume={129 1-2},
When intraorally infused with a flavored solution previously paired with an emetic drug, rats display a characteristic gaping reaction that reflects conditioned nausea in this species that is unable to vomit. The commonly used conditioned taste avoidance measure, is not a selective measure of nausea because nearly every drug tested (even rewarding drugs) is capable of producing a conditioned taste avoidance. In contrast, only emetic drugs produce conditioned gaping reactions in rats, and anti… CONTINUE READING

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