Conditioned Enhancement of Antibody Production Is Disrupted by Insular Cortex and Amygdala but Not Hippocampal Lesions

@article{RamirezAmaya1999ConditionedEO,
  title={Conditioned Enhancement of Antibody Production Is Disrupted by Insular Cortex and Amygdala but Not Hippocampal Lesions},
  author={V. Ramirez-Amaya and F. Berm{\'u}dez-Rattoni},
  journal={Brain, Behavior, and Immunity},
  year={1999},
  volume={13},
  pages={46-60}
}
  • V. Ramirez-Amaya, F. Bermúdez-Rattoni
  • Published 1999
  • Biology, Medicine
  • Brain, Behavior, and Immunity
  • Pavlovian conditioning procedures can be used to activate the immune system. A reliable conditioned increase of antibody production can be obtained in rats that have previously received a gustative or odor stimulus as the conditioned stimulus paired with an antigen, by exposing the animals to the conditioned stimulus alone. We showed evidence that an excitotoxic lesion bilaterally applied into the insular cortex or the amygdala, but not into the dorsal hippocampus, impaired the acquisition of… CONTINUE READING
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