Conditional independence mapping of DIGE data reveals PDIA3 protein species as key nodes associated with muscle aerobic capacity

@inproceedings{Burniston2014ConditionalIM,
  title={Conditional independence mapping of DIGE data reveals PDIA3 protein species as key nodes associated with muscle aerobic capacity},
  author={Jatin G Burniston and Jenna Kenyani and Donna Gray and Eleonora Guadagnin and Ian H. Jarman and James N Cobley and Daniel J Cuthbertson and Yi-Wen Chen and Jonathan M. Wastling and Paulo J G Lisboa and Lauren G Koch and Steven Loyal Britton},
  booktitle={Journal of proteomics},
  year={2014}
}
UNLABELLED Profiling of protein species is important because gene polymorphisms, splice variations and post-translational modifications may combine and give rise to multiple protein species that have different effects on cellular function. Two-dimensional gel electrophoresis is one of the most robust methods for differential analysis of protein species, but bioinformatic interrogation is challenging because the consequences of changes in the abundance of individual protein species on cell… CONTINUE READING
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Efficient identification of independence networks using mutual information

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