Condensin promotes the juxtaposition of DNA flanking its loading site in Bacillus subtilis.

@article{Wang2015CondensinPT,
  title={Condensin promotes the juxtaposition of DNA flanking its loading site in Bacillus subtilis.},
  author={Xindan Wang and Tung B K Le and Bryan R. Lajoie and Job Dekker and Michael T Laub and David Z Rudner},
  journal={Genes & development},
  year={2015},
  volume={29 15},
  pages={1661-75}
}
SMC condensin complexes play a central role in compacting and resolving replicated chromosomes in virtually all organisms, yet how they accomplish this remains elusive. In Bacillus subtilis, condensin is loaded at centromeric parS sites, where it encircles DNA and individualizes newly replicated origins. Using chromosome conformation capture and cytological assays, we show that condensin recruitment to origin-proximal parS sites is required for the juxtaposition of the two chromosome arms… CONTINUE READING
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