Condensin I Recruitment to Base Damage-Enriched DNA Lesions Is Modulated by PARP1

Abstract

Condensin I is important for chromosome organization and segregation in mitosis. We previously showed that condensin I also interacts with PARP1 in response to DNA damage and plays a role in single-strand break repair. However, whether condensin I physically associates with DNA damage sites and how PARP1 may contribute to this process were unclear. We found… (More)
DOI: 10.1371/journal.pone.0023548

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