Concurrent occurrence of gastric adenocarcinoma and duodenal neuroendocrine cell carcinoma: a composite tumour or collision tumours ?

@article{Fukui2001ConcurrentOO,
  title={Concurrent occurrence of gastric adenocarcinoma and duodenal neuroendocrine cell carcinoma: a composite tumour or collision tumours ?},
  author={Hirokazu Fukui and Milioni Takada and Toshimi Chiba and Ryo Kashiwagi and Michiko Sakane and Futoshi Tabata and Yousuke Kuroda and Yo Ueda and Hitoshi Kawamata and Johji Imura and Takahiro Fujimori},
  journal={Gut},
  year={2001},
  volume={48 6},
  pages={
          853-6
        }
}
BACKGROUND Neuroendocrine cell (NEC) carcinoma is occasionally accompanied by adenocarcinoma but the relationship between these two morphologically distinct tumours is unclear. Two hypotheses have arisen regarding the mechanism for the association of adenocarcinoma and NEC carcinoma. One is that both are derived from a common multipotential epithelial stem cell. The second hypothesis is that adenocarcinoma and NEC carcinoma arise from a multipotential epithelial stem cell and a primitive NEC… CONTINUE READING
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