Concurrent mood and anxiety disorders are associated with pharmacoresistant seizures in patients with MTLE

@article{Nogueira2017ConcurrentMA,
  title={Concurrent mood and anxiety disorders are associated with pharmacoresistant seizures in patients with MTLE},
  author={Mateus Henrique Nogueira and Clarissa Lin Yasuda and Ana Carolina Coan and Andres M. Kanner and Fernando Cendes},
  journal={Epilepsia},
  year={2017},
  volume={58}
}
To investigate whether mood disorders (MD) and anxiety disorders (AD) are associated with seizure control in patients with mesial temporal lobe epilepsy (MTLE). We compared patients without any current psychiatric disorder, patients with current MD and/or AD, patients with subsyndromic depression episodes (SSDE) and anxiety episodes (SSAE), and patients with family psychiatric history. 

Depressive disorders in patients with pharmaco-resistant mesial temporal lobe epilepsy

Depressive disorders are common, underdiagnosed and undertreated in patients with refractory MTLE, and no significant difference was found between patients with and without depression and the presence of HA.

Epilepsy and anxiety.

  • M. TuftO. HenningK. Nakken
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    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke
  • 2018
Up to one-quarter of people with epilepsy have mental health disorders in addition to seizures, and psychiatric symptoms can reduce quality of life more than epileptic seizures.

Psychiatric Comorbidities in People With Epilepsy.

All patients with epilepsy should be routinely screened for psychiatric disorder at the onset and at least once a year, and patients and their relatives should be informed of the risk of mental health problems and the implications.

Epilepsy and mood disorders

  • M. Mula
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    The Comorbidities of Epilepsy
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Neuropsychiatric Treatments for Epilepsy: Nonpharmacological Approaches.

An overview of non-pharmacological treatments currently available to patients with epilepsy (PWE) are provided-and their effect on mood and anxiety disorders as well as epilepsy is reviewed.

Major Depressive Disorder Associated With Reduced Cortical Thickness in Women With Temporal Lobe Epilepsy

The identification of areas with reduced CT and atrophy of the ipsilateral amygdala in women with MTLE and MDD suggest that the cortical thinning in the network of the paralimbic system is related to the co-occurrence and intensity of depressive symptoms in this group.

Worrying More about Anxiety in Patients with Epilepsy

Validated instruments such as the Generalized Anxiety Disorder, Hospital Anxiety and Depression Scale, the Patient Health Questionnaire-9, or Neurologic Disorders Depression Inventory for Epilepsy (NDDI-E) are important for neurologists to incorporate into their regular visits in order to formally screen their patients and uncover who is at higher risk of harm and who needs treatment, although there are likely systems reasons that this is generally not done.

Common psychiatric comorbidities in epilepsy: How big of a problem is it?

...

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