Concurrent modulation of anxiety and memory.

  title={Concurrent modulation of anxiety and memory.},
  author={P. M. Lyons Wall and Claude Messier},
  journal={Behavioural brain research},
  volume={109 2},
We have previously shown that the ventromedial prefrontal cortex (vmPFC) is involved in spontaneous working memory and anxiety-related behaviour in CD-1 mice. Specifically, pretrial microinjection of the kappa(1) agonist, U-69,593, in the infralimbic (IL) area of the vmPFC produced a robust anxiolytic behavioural profile in the elevated plus-maze and enhanced spontaneous working memory in the Y-maze. In the present study we sought to determine whether these effects were specific to IL kappa… CONTINUE READING

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