Concurrent chemoradiotherapy with a novel fluoropyrimidine, S-1, and cisplatin for locally advanced esophageal cancer: long-term results of a phase II trial.

@article{Iwase2013ConcurrentCW,
  title={Concurrent chemoradiotherapy with a novel fluoropyrimidine, S-1, and cisplatin for locally advanced esophageal cancer: long-term results of a phase II trial.},
  author={Hiroaki Iwase and Masaaki Shimada and Tomoyuki Tsuzuki and Noboru Hirashima and Masayuki Okeya and Yusuke Hibino and Nobumitsu Ryuge and Misaki Yokoi and Yuichi Kida and Takeshi Kuno and Yusaku Tanaka and Bunichiro Kato and Masaya Esaki and Noboru Urata and Eriko Kato},
  journal={Oncology},
  year={2013},
  volume={84 6},
  pages={342-9}
}
OBJECTIVES A phase II study was performed to investigate the safety and efficacy of concurrent chemoradiotherapy (CCRT) combined with an orally active fluoropyrimidine, S-1, plus cisplatin for locally advanced esophageal cancer (LAEC). METHODS CCRT comprised 2 courses, a 30-Gy radiotherapy over 3 weeks plus daily oral S-1 (80 mg/m(2)/day) for 2 weeks and a 24-hour cisplatin infusion (70 mg/m(2)) on day 8, and an identical course administered after a 2-week break. RESULTS One hundred and… CONTINUE READING

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Concurrent chemoradiotherapy with a novel fluoropyrimidine , S-1 , and cisplatin for locally advanced esophageal cancer : long - term results of a phase II trial .
A phase II study was performed to investigate the safety and efficacy of concurrent chemoradiotherapy ( CCRT ) combined with an orally active fluoropyrimidine , S-1 , plus cisplatin for locally advanced esophageal cancer ( LAEC ) .
A phase II study was performed to investigate the safety and efficacy of concurrent chemoradiotherapy ( CCRT ) combined with an orally active fluoropyrimidine , S-1 , plus cisplatin for locally advanced esophageal cancer ( LAEC ) .
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