Concordance of two multiple analytical approaches demonstrate that interaction between BMI and ADIPOQ haplotypes is a determinant of LDL cholesterol in a general French population

@article{Vasseur2010ConcordanceOT,
  title={Concordance of two multiple analytical approaches demonstrate that interaction between BMI and ADIPOQ haplotypes is a determinant of LDL cholesterol in a general French population},
  author={Francis Vasseur and Thomas Caeyseele and Mouna Barat-Houari and St{\'e}phane Lobbens and Aline Meirhaeghe and David Meyre and Philippe Froguel and Philippe Amouyel and Nicole Helbecque},
  journal={Journal of Human Genetics},
  year={2010},
  volume={55},
  pages={227-231}
}
Genetic and environmental factors are involved in insulin resistance (IR). IR and dyslipidemia associate with increased risk of cardiovascular diseases. Plasma low-density lipoprotein cholesterol (LDL-C) level is a marker of cardiovascular risk. In a Caucasian general population we aimed at determining the multifactorial components of LDL-C levels using 10 genes and 3 phenotypes. In the PPARG, UCP3, ADIPOQ, TNF, LIPC, CARTPT, PCSK9, SCAP, SCARB1 and ENPP1 genes known to be associated with IR or… CONTINUE READING