Concordance of positive and negative symptoms in coaffected sib-pairs with schizophrenia.

  title={Concordance of positive and negative symptoms in coaffected sib-pairs with schizophrenia.},
  author={Hai G. Hwu and Yen Ching Wu and Sandy F-C Lee and Lan Lan Liang Yeh and Shangjr Gwo and Howard C. Hsu and Chee Jen Chang and W J Chen},
  journal={American journal of medical genetics},
  volume={74 1},
Positive and negative symptom (NGS) dimensions were examined for their concordance in 46 coaffected schizophrenic sib-pairs. Results showed that the symptom dimensions of negative symptoms (NGS), delusion-hallucination (DHS), and thought disorganization (TDS) could be formulated. Discrete genetic endowment of these three symptom dimensions was not found as shown by the low concordance in sib pair analysis (kappa = 0.20-0.30). Thirty-seven pairs (80.4%) and 21 pairs (45.7%) had liability… CONTINUE READING


Publications citing this paper.


Publications referenced by this paper.
Showing 1-10 of 39 references

Negative symptom at discharge predicts poor outcome

  • HG Hwu, H Tan, CC Chen
  • Br J Psychiat
  • 1995
2 Excerpts

Positive and negative symptoms

  • NC Andreasen, MA Roy, M Flaum
  • In Hirsch SR, Weinberger DR (eds): “Schizophrenia…
  • 1995
1 Excerpt

Positive and negative syndromes in families with schizophrenia

  • AS Bassett, EJ Collins, SE Nattall, WG Honer
  • Schizoph Res
  • 1993
1 Excerpt

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