Concordance across species in the reproductive and developmental toxicity of tetrachloroethylene.

@article{Beliles2002ConcordanceAS,
  title={Concordance across species in the reproductive and developmental toxicity of tetrachloroethylene.},
  author={Robert P. Beliles},
  journal={Toxicology and industrial health},
  year={2002},
  volume={18 2},
  pages={91-106}
}
Reproductive and developmental toxicities resulting from exposure to tetrachloroethylene include delayed or impaired conception, sperm quality, death during development, developmental neurotoxicity, and growth retardation. In most cases there was concordance between rodents and humans. The risk assessments indicated that neurotoxicity was the most sensitive endpoint for inhalation, whereas growth retardation was the most sensitive endpoint when exposure was by the oral route. The reference… CONTINUE READING