Concomitant use of clopidogrel and proton pump inhibitors: impact on platelet function and clinical outcome- a systematic review

@article{Focks2012ConcomitantUO,
  title={Concomitant use of clopidogrel and proton pump inhibitors: impact on platelet function and clinical outcome- a systematic review},
  author={Jeroen Jaspers Focks and Marc A. Brouwer and Martijn G H van Oijen and {\'A}ngel Lanas and Deepak L. Bhatt and Freek W. A. Verheugt},
  journal={Heart},
  year={2012},
  volume={99},
  pages={520 - 527}
}
  • Jeroen Jaspers Focks, Marc A. Brouwer, +3 authors Freek W. A. Verheugt
  • Published 2012
  • Medicine
  • Heart
  • Background Clopidogrel as an adjunct to aspirin has improved outcomes after acute coronary syndromes, but laboratory studies suggest a reduced antiplatelet effect when proton pump inhibitors (PPIs) are co-administered. Despite corroborating data from retrospective studies, new clinical data fuel the controversy on this issue. Purpose Systematic review of the impact of the addition of PPIs to clopidogrel on platelet function and cardiovascular outcome. Data sources PubMed, Web-of-Science… CONTINUE READING

    Citations

    Publications citing this paper.
    SHOWING 1-10 OF 81 CITATIONS, ESTIMATED 45% COVERAGE

    FILTER CITATIONS BY YEAR

    2011
    2020

    CITATION STATISTICS

    • 2 Highly Influenced Citations

    References

    Publications referenced by this paper.
    SHOWING 1-10 OF 93 REFERENCES

    Proton pump inhibitors in patients treated with aspirin and clopidogrel after acute coronary syndrome.

    • António Gaspar, Sílvia Ribeiro, +6 authors Adelino Correia
    • Medicine
    • Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology
    • 2010