Concomitant AD pathology affects clinical manifestation and survival in dementia with Lewy bodies.

@article{Lemstra2017ConcomitantAP,
  title={Concomitant AD pathology affects clinical manifestation and survival in dementia with Lewy bodies.},
  author={Afina W. Lemstra and Marlijn H de Beer and Charlotte E Teunissen and Charlotte Schreuder and P. Scheltens and W. M. van der Flier and Sietske A. M. Sikkes},
  journal={Journal of neurology, neurosurgery, and psychiatry},
  year={2017},
  volume={88 2},
  pages={
          113-118
        }
}
OBJECTIVE To investigate whether concomitant Alzheimer's disease (AD) pathology, reflected by cerebrospinal fluid (CSF) biomarkers, has an impact on dementia with Lewy bodies (DLB) in terms of clinical presentation, cognitive decline, nursing home admittance and survival. PARTICIPANTS We selected 111 patients with probable DLB and CSF available from the Amsterdam Dementia Cohort. On the basis of the AD biomarker profile (CSF tau/amyloid-β 1-42 (Aβ42) ratio >0.52), we divided patients into a… CONTINUE READING

Citations

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Clinical Presentation, Diagnostic Features, and Mortality in Dementia with Lewy Bodies.

  • Journal of Alzheimer's disease : JAD
  • 2019
VIEW 2 EXCERPTS
CITES RESULTS & BACKGROUND

Current state of Alzheimer’s fluid biomarkers

  • Acta Neuropathologica
  • 2018
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CITES BACKGROUND

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