Concise total synthesis of spirocurcasone.

  title={Concise total synthesis of spirocurcasone.},
  author={Hideki Abe and Akimi Sato and Toyoharu Kobayashi and Hisanaka Ito},
  journal={Organic letters},
  volume={15 6},
A concise total synthesis of spirocurcasone was accomplished. Key features of the synthesis involved a vinylogous Mukaiyama aldol reaction, a Carroll rearrangement of β-keto allyl ester derivative, an intramolecular aldol condensation, and a spiro ring formation by ring-closing metathesis of the pentaene compound. This synthetic work was complete in nine steps from (S)- or (R)-perillaldehyde without the use of protecting groups. Interestingly, the optical rotation of the synthetic… 
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