Concise strategy to the core structure of the macrolide queenslandon.

  title={Concise strategy to the core structure of the macrolide queenslandon.},
  author={Anton S. Khartulyari and Manmohan Kapur and Martin E. Maier},
  journal={Organic letters},
  volume={8 25},
The fully functionalized core structure of the macrolactone queenslandon was prepared using a novel strategy consisting of a glycolate aldol reaction and hydroboration of the derived enol ether 17 followed by Suzuki cross-coupling with an iodostyrene. After conversion of the cross-coupling product to the seco acid 22, Mitsunobu macrolactonization and protecting group manipulations led to the queenslandon model 5. [structure: see text] 
15 Citations
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