Concise review: the potential of stromal cell-derived factor 1 and its receptors to promote stem cell functions in spinal cord repair.

@article{Jaerve2012ConciseRT,
  title={Concise review: the potential of stromal cell-derived factor 1 and its receptors to promote stem cell functions in spinal cord repair.},
  author={Anne Jaerve and Jessica Schira and Hans Werner M{\"u}ller},
  journal={Stem cells translational medicine},
  year={2012},
  volume={1 10},
  pages={732-9}
}
Transplanted stem cells provide beneficial effects on regeneration/recovery after spinal cord injury (SCI) by the release of growth-promoting factors, increased tissue preservation, and provision of a permissive environment for axon regeneration. A rise in chemokine stromal cell-derived factor 1 (SDF-1/CXCL12) expression levels in central nervous system (CNS) injury sites has been shown to play a central role in recruiting transplanted stem cells. Although technically more challenging, it has… CONTINUE READING
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