Concise review: stem cell effects in radiation risk.

  title={Concise review: stem cell effects in radiation risk.},
  author={Kevin M Prise and Anna Saran},
  journal={Stem cells},
  volume={29 9},
Stem cells of normal mammalian tissues are defined as nonspecialized cells that have two critical properties: (a) the ability to renew themselves through cell division and (b) the potency to differentiate into other cell types. Therefore, they play a crucial role in development and in tissue homeostasis during adult life. Being long-lived, they can be the targets of environmental carcinogens leading to the accumulation of consecutive genetic changes. Hence, the genome of stem cells must be… CONTINUE READING
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