Concise review: pursuing self-renewal and pluripotency with the stem cell factor Nanog.

@article{Saunders2013ConciseRP,
  title={Concise review: pursuing self-renewal and pluripotency with the stem cell factor Nanog.},
  author={Arven H Saunders and Francesco Faiola and Jianlong Wang},
  journal={Stem cells},
  year={2013},
  volume={31 7},
  pages={1227-36}
}
Pluripotent embryonic stem cells and induced pluripotent stem cells hold great promise for future use in tissue replacement therapies due to their ability to self-renew indefinitely and to differentiate into all adult cell types. Harnessing this therapeutic potential efficiently requires a much deeper understanding of the molecular processes at work within the pluripotency network. The transcription factors Nanog, Oct4, and Sox2 reside at the core of this network, where they interact and… CONTINUE READING
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