Concise review: combining human leukocyte antigen G and mesenchymal stem cells for immunosuppressant biotherapy.

Abstract

Both human leukocyte antigen G (HLA-G) and multipotential mesenchymal stem/stromal cells (MSCs) exhibit immunomodulatory functions. In allogeneic tranplantation, the risks of acute and chronic rejection are still high despite improvement in immunosuppressive treatments, and the induction of a state of tolerance to alloantigens is not achieved… (More)
DOI: 10.1002/stem.1494

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