Concise Review: Evidence for CD34 as a Common Marker for Diverse Progenitors

  title={Concise Review: Evidence for CD34 as a Common Marker for Diverse Progenitors},
  author={Laura E Sidney and Matthew James Branch and Siobh{\'a}n E. Dunphy and Harminder S Dua and Andrew Hopkinson},
  booktitle={Stem cells},
CD34 is a transmembrane phosphoglycoprotein, first identified on hematopoietic stem and progenitor cells. Clinically, it is associated with the selection and enrichment of hematopoietic stem cells for bone marrow transplants. Due to these historical and clinical associations, CD34 expression is almost ubiquitously related to hematopoietic cells, and it is a common misconception that CD34-positive (CD34(+) ) cells in nonhematopoietic samples represent hematopoietic contamination. The prevailing… CONTINUE READING
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