Concerted control of Escherichia coli cell division.

  title={Concerted control of Escherichia coli cell division.},
  author={Matteo Osella and Eileen Nugent and Marco Cosentino Lagomarsino},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  volume={111 9},
The coordination of cell growth and division is a long-standing problem in biology. Focusing on Escherichia coli in steady growth, we quantify cell division control using a stochastic model, by inferring the division rate as a function of the observable parameters from large empirical datasets of dividing cells. We find that (i) cells have mechanisms to control their size, (ii) size control is effected by changes in the doubling time, rather than in the single-cell elongation rate, (iii) the… CONTINUE READING
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