Concerted action of tenascin-C domains in cell adhesion, anti-adhesion and promotion of neurite outgrowth.


We used a new approach to identify domains of chicken tenascin-C required for interaction with cells. Instead of expressing the parts of interest, we deleted them from an otherwise intact tenascin-C molecule and scored for the concomitant change in activity. As a starting point for all mutant constructs we expressed the smallest naturally occurring tenascin… (More)


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