Concerted Action of Two Formins in Gliding Motility and Host Cell Invasion by Toxoplasma gondii

@inproceedings{Daher2010ConcertedAO,
  title={Concerted Action of Two Formins in Gliding Motility and Host Cell Invasion by Toxoplasma gondii},
  author={Wassim Daher and Fabienne Plattner and M. Carlier and Dominique Soldati-Favre},
  booktitle={PLoS pathogens},
  year={2010}
}
The invasive forms of apicomplexan parasites share a conserved form of gliding motility that powers parasite migration across biological barriers, host cell invasion and egress from infected cells. Previous studies have established that the duration and direction of gliding motility are determined by actin polymerization; however, regulators of actin dynamics in apicomplexans remain poorly characterized. In the absence of a complete ARP2/3 complex, the formin homology 2 domain containing… CONTINUE READING

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