Concepts for systemic treatment of micrometastases

@article{Schabel1975ConceptsFS,
  title={Concepts for systemic treatment of micrometastases},
  author={F. Schabel},
  journal={Cancer},
  year={1975},
  volume={35}
}
If total tumor cell kill is a requirement for “cure,” as it probably is for at least some tumors, treatment of micrometastases containing ≦ 106 viable tumor cells is a problem facing all cancer therapists. Metastatic tumor cell foci of ≦ 106 cells, particularly if widely disseminated, are, in the main, grossly undetectable and are, therefore, the proper targets for the chemotherapist and the immunotherapist. Current knowledge of tumor cell population growth kinetics indicates that the growth… Expand
Concepts for treatment of micrometastases developed in murine systems.
  • F. Schabel
  • Medicine
  • AJR. American journal of roentgenology
  • 1976
Systemic treatment of breast cancer: past, present and future.
  • P. Carbone
  • Medicine
  • International journal of radiation oncology, biology, physics
  • 1976
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