• DOI:10.1016/j.steroids.2003.08.008
Corpus ID: 41756726

Conception and pharmacodynamic profile of drospirenone

@article{Elger2003ConceptionAP,
  title={Conception and pharmacodynamic profile of drospirenone},
  author={W. Elger and S. Beier and K. Pollow and R. Garfield and A. Hillisch},
  journal={Steroids},
  year={2003},
  volume={68},
  pages={891-905}
}

W. Elger, S. Beier, +2 authors A. Hillisch

Published 2003

Medicine

Steroids

Progesterone is more than a progestin. Beyond functions in cycle and pregnancy, progesterone binds with high affinity to the mineralocorticoid receptor (MR) acting as an antagonist, with obvious significance for electrolyte homeostasis, an array of MR-related functions in the circulation as well as in the CNS. Progesterone induces natriuresis at physiological concentrations. Lack of antimineralocorticoid activity with conventional progestins may account for sodium and water retention, minor… CONTINUE READING

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