Concentric demyelination by self-organization: a new hypothesis for Baló's sclerosis

@article{Khonsari2007ConcentricDB,
  title={Concentric demyelination by self-organization: a new hypothesis for Bal{\'o}'s sclerosis},
  author={Roman Hossein Khonsari and Vincent Calvez},
  journal={Nature Clinical Practice Neurology},
  year={2007},
  volume={3},
  pages={E1-E1}
}
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ncbi.nlm.nih.gov
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    References

    SHOWING 1-5 OF 5 REFERENCES
    Technology Insight: can neuroimaging provide insights into the role of ischemia in Baló's concentric sclerosis?
    TLDR
    Evidence from longitudinal neuroimaging studies that supports the role of ischemic preconditioning in Baló's concentric sclerosis is discussed.
    The Origins of Concentric Demyelination: Self-Organization in the Human Brain
    TLDR
    A robust mathematical model is proposed for Baló's sclerosis, sharing common molecular and cellular mechanisms with multiple sclerosis, and homogeneous and concentric demyelinations may be two different macroscopic outcomes of a single fundamental immune disorder.
    Tissue preconditioning may explain concentric lesions in Baló's type of multiple sclerosis.
    TLDR
    Investigation of immunopathology in autopsy tissue of 14 patients with acute multiple sclerosis or fulminant exacerbations of chronic multiple sclerosis with Baló-type lesions in the CNS found that all active concentric lesions followed a pattern of demyelination that bears resemblances to hypoxia-like tissue injury.
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