Concentrations of the Carcinogen 4-(Methylnitrosamino)-1-(3-Pyridyl)-1-Butanone in Sidestream Cigarette Smoke Increase after Release into Indoor Air: Results from Unpublished Tobacco Industry Research
@article{Schick2007ConcentrationsOT, title={Concentrations of the Carcinogen 4-(Methylnitrosamino)-1-(3-Pyridyl)-1-Butanone in Sidestream Cigarette Smoke Increase after Release into Indoor Air: Results from Unpublished Tobacco Industry Research}, author={S. Schick and S. Glantz}, journal={Cancer Epidemiology Biomarkers & Prevention}, year={2007}, volume={16}, pages={1547 - 1553} }
Research has shown that the toxicity of sidestream cigarette smoke, the primary constituent of secondhand smoke, increases over time. To find potential mechanisms that would explain the increase in sidestream smoke toxicity over time, we analyzed unpublished research reports from Philip Morris Co. using the internal tobacco industry documents now available at the University of California San Francisco Legacy Tobacco Documents Library and other Web sites. Unpublished research from Philip Morris… CONTINUE READING
Figures, Tables, and Topics from this paper
53 Citations
Formation of carcinogens indoors by surface-mediated reactions of nicotine with nitrous acid, leading to potential thirdhand smoke hazards
- Chemistry, Medicine
- Proceedings of the National Academy of Sciences
- 2010
- 298
- PDF
Evaluation of tobacco specific nitrosamines exposure by quantification of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in human hair of non-smokers
- Chemistry, Medicine
- Scientific reports
- 2016
- 7
- PDF
Urine Cotinine Underestimates Exposure to the Tobacco-Derived Lung Carcinogen 4-(Methylnitrosamino)-1-(3-Pyridyl)-1-Butanone in Passive Compared with Active Smokers
- Medicine
- Cancer Epidemiology, Biomarkers & Prevention
- 2010
- 24
- PDF
Extensive Metabolic Activation of the Tobacco-Specific Carcinogen 4-(Methylnitrosamino)-1-(3-Pyridyl)-1-Butanone in Smokers
- Chemistry, Medicine
- Cancer Epidemiology Biomarkers & Prevention
- 2008
- 49
- PDF
Comparison of urine cotinine and the tobacco-specific nitrosamine metabolite 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) and their ratio to discriminate active from passive smoking.
- Chemistry, Medicine
- Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco
- 2011
- 100
Exposure to nitrosamines in thirdhand tobacco smoke increases cancer risk in non-smokers.
- Chemistry, Medicine
- Environment international
- 2014
- 57
- PDF
Consequences of Incomplete Smoke-Free Legislation in the Republic of Korea: Results from Environmental and Biochemical Monitoring: Community Based Study
- Medicine
- Cancer research and treatment : official journal of Korean Cancer Association
- 2016
- 3
Thirdhand Smoke at Philip Morris.
- Medicine
- Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco
- 2018
- 3
References
SHOWING 1-10 OF 70 REFERENCES
Tobacco-specific N-nitrosamines and Areca-derived N-nitrosamines: chemistry, biochemistry, carcinogenicity, and relevance to humans.
- Chemistry, Medicine
- Journal of toxicology and environmental health
- 1994
- 332
Formation and analysis of tobacco-specific N-nitrosamines.
- Chemistry, Medicine
- Critical reviews in toxicology
- 1996
- 81
Carcinogen derived biomarkers: applications in studies of human exposure to secondhand tobacco smoke
- Medicine
- Tobacco Control
- 2004
- 68
- Highly Influential
- PDF
Sidestream cigarette smoke toxicity increases with aging and exposure duration
- Medicine, Chemistry
- Tobacco Control
- 2006
- 67
Philip Morris toxicological experiments with fresh sidestream smoke: more toxic than mainstream smoke
- Medicine
- Tobacco Control
- 2005
- 222
- PDF
SUBCHRONIC INHALATION STUDY IN RATS USING AGED AND DILUTED SIDESTREAM SMOKE FROM A REFERENCE CIGARETTE
- Medicine
- 1993
- 43
The carcinogenic potential of the gas phase of environmental tobacco smoke.
- Medicine
- Carcinogenesis
- 1997
- 139
- PDF
Respirable Particles and Carcinogens in the Air of Delaware Hospitality Venues Before and After a Smoking Ban
- Environmental Science, Medicine
- Journal of occupational and environmental medicine
- 2004
- 224
- PDF
Lung Tumor Response in Strain a Mice Exposed to Tobacco Smoke: Some Dose-Effect Relationships
- Chemistry, Medicine
- Inhalation toxicology
- 2004
- 24