Concentrations of mezlocillin in the serum, heart valves, muscle and subcutaneous tissue of patients undergoing open-heart surgery.

Abstract

4 g mezlocillin as a five-minute intravenous bolus were given preoperatively to 31 adult patients undergoing open-heart surgery. Mezlocillin serum levels declined from 42.8 mg/l at 1-2 h after injection to less than 1 mg/l at 6-8 h after application. Concentrations in muscle and subcutaneous tissue varied between 18 micrograms/g and less than 1 microgram/g… (More)

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Cite this paper

@article{Daschner1985ConcentrationsOM, title={Concentrations of mezlocillin in the serum, heart valves, muscle and subcutaneous tissue of patients undergoing open-heart surgery.}, author={Franz D. Daschner and H. M. Just and Ines Kappstein and H Spillner and Victoria Margot Schlosser}, journal={Infection}, year={1985}, volume={13 4}, pages={182-3} }