Concentration dependence of currents through single sodium-selective pores in frog skin

@article{Driessche1979ConcentrationDO,
  title={Concentration dependence of currents through single sodium-selective pores in frog skin},
  author={Willy Van Driessche and Bernd Lindemann},
  journal={Nature},
  year={1979},
  volume={282},
  pages={519-520}
}
Many transport processes in biological membranes show a saturation of transport rate when the concentration of the transported ions or molecules is sufficiently increased. Saturation will result when at high concentrations a translocation step which does not directly depend on bulk concentration becomes rate limiting, and it is expected for all multi-step translocation mechanisms. However, a possible alternative explanation for saturation is a regulatory process which decreases the number of… CONTINUE READING

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