Concentrating hormones into secretory granules: layers of control

  title={Concentrating hormones into secretory granules: layers of control},
  author={Priscilla S. Dannies},
  journal={Molecular and Cellular Endocrinology},
Soluble protein hormones are concentrated and stored in secretory granules The cisternal maturation model for transport of proteins through the Golgi complex allows a major role for formation of reversible aggregates as a means of both concentrating and sorting hormones, since soluble proteins will be removed in small vesicles, leaving behind the aggregated hormones. The storage of secretory granule proteins, however, is more selective than would be expected if passive aggregation were the only… CONTINUE READING


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