Concanavalin A induces an intraluminal alkalinization of thymocyte membrane vesicles.

@article{Mikkelsen1980ConcanavalinAI,
  title={Concanavalin A induces an intraluminal alkalinization of thymocyte membrane vesicles.},
  author={Ross B. Mikkelsen and Rupert Schmidt-Ullrich and Donald F. H. Wallach},
  journal={Journal of cellular physiology},
  year={1980},
  volume={102 2},
  pages={113-7}
}
Weak acid distribution methods demonstrate that mitogenic levels of concanavalin A induce an intravesicular alkalinization of isolated thymocyte membrane vesicles. Experiments with chemical reagents that crosslink the high affinity concanavalin A receptor and extensive correlation with known cellular events suggest that a "membrane Bohr effect" may participate in the initiation of mitogenesis.