Concanavalin A induces an intraluminal alkalinization of thymocyte membrane vesicles.

Abstract

Weak acid distribution methods demonstrate that mitogenic levels of concanavalin A induce an intravesicular alkalinization of isolated thymocyte membrane vesicles. Experiments with chemical reagents that crosslink the high affinity concanavalin A receptor and extensive correlation with known cellular events suggest that a "membrane Bohr effect" may… (More)

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