Concanavalin A (NSC-143504): its action on experimental tumor cells and possible use in cancer chemotherapy.


Concanavalin A administered to mice kills KHT fibrosarcoma tumor cells and, less markedly, AKR lymphoma cells at doses where it has no effect on numbers of normal hematopoietic colony-forming cells. Concanavalin A in vitro agglutinates suspensions of cells prepared from murine and human tumors but does not agglutinate suspensions prepared from most normal… (More)


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