Computing Ka and Ks with a consideration of unequal transitional substitutions

@article{Zhang2006ComputingKA,
  title={Computing Ka and Ks with a consideration of unequal transitional substitutions},
  author={Zhang Zhang and Jun Li and Jun Jie Yu},
  journal={BMC Evolutionary Biology},
  year={2006},
  volume={6},
  pages={44 - 44}
}
Approximate methods for estimating nonsynonymous and synonymous substitution rates (Ka and Ks) among protein-coding sequences have adopted different mutation (substitution) models. In the past two decades, several methods have been proposed but they have not considered unequal transitional substitutions (between the two purines, A and G, or the two pyrimidines, T and C) that become apparent when sequences data to be compared are vast and significantly diverged. We propose a new method (MYN), a… CONTINUE READING
Highly Cited
This paper has 125 citations. REVIEW CITATIONS

Citations

Publications citing this paper.
Showing 1-10 of 43 extracted citations

126 Citations

01020'08'11'14'17
Citations per Year
Semantic Scholar estimates that this publication has 126 citations based on the available data.

See our FAQ for additional information.

References

Publications referenced by this paper.
Showing 1-10 of 28 references

33(Database issue):D447-53

T Hubbard, D Andrews, +49 authors E Birney
Ensembl • 2005
View 1 Excerpt

Similar Papers

Loading similar papers…