Computerized detection and segmentation of mitochondria on electron microscope images.

@article{Mumcuoglu2012ComputerizedDA,
  title={Computerized detection and segmentation of mitochondria on electron microscope images.},
  author={Erkan U. Mumcuoglu and Reza Hassanpour and Serdar F. Tasel and Guy C. Perkins and Maryann E. Martone and Metin Nafi Gurcan},
  journal={Journal of microscopy},
  year={2012},
  volume={246 3},
  pages={248-65}
}
Mitochondrial function plays an important role in the regulation of cellular life and death, including disease states. Disturbance in mitochondrial function and distribution can be accompanied by significant morphological alterations. Electron microscopy tomography (EMT) is a powerful technique to study the 3D structure of mitochondria, but the automatic detection and segmentation of mitochondria in EMT volumes has been challenging due to the presence of subcellular structures and imaging… CONTINUE READING